Versatile Peptide Discovery Platform
An unbiased, ultra-versatile system that unlocks novel multi-cyclic peptides and small molecules, built upon 35+ years of continuous innovation.
Platform Advantages
Detailed Technologies & Research Breakthroughs
Pioneering methodologies that have shaped the landscape of peptide discovery and screening
Pioneered the OBOC Technology
protein-binding ligand discovery (Lam et al.).
Nature 354 (6348):82-84
Cell Binding/Targeting Assays
This technology isolates peptides binding to live cell surface receptors, enabling screening of conformationally sensitive receptors and selecting specific interactions with function-blocking antibodies.
DU-H prostate carcinoma cell attachment to peptide beads
Mol Divers 2 (1-2):19-28.
High-Throughput Screening with Microwell Technology
A powerful system for ultra-high-throughput, in situ, releasable solution-phase cell-based screening of functional molecules.
Townsend, J Comb Chem 12 (5):700-712. In-situ release of surface bound compound from dipeptide-based peptidomimetic library and resulting MTT cell viability assay.
High-Throughput Screening with Microfluidics/Magnetics
This powerful technology presents a simple, cost-effective, and reliable automated platform for high-throughput magnetic sorting of large particles.
Cho et al., Price et al. ACS Comb Sci 18 (6):271-278.
Sophisticated One-Bead-Two-Compound Combinatorial Library
Rapidly discovers molecules that modulate cell signaling by screening live cells on bead surfaces. Demonstrated in discovering 'death ligands' for lymphoma cells.
Kumaresan PR, ACS Comb Sci 13 (3):259-264
Multiplex Library-Against-Library Screening
Rapid discovery of functional molecular ligands (small molecule or peptides) against proteomic targets
Wu CY, ACS Comb Sci 18 (6):320-329
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Our cutting-edge platforms are designed to accelerate drug discovery and delivery. Join us in creating the next generation of precision therapeutics.