The NovaCode Advantage

Our unique strengths position us at the forefront of therapeutic innovation

Our Core Advantages

Pioneering Platforms

Innovative discovery and delivery systems.

Decades of Expertise

35+ years of continuous scientific innovation.

Targeted Solutions

Addressing unreachable disease drivers effectively.

Collaborative Approach

Partnering to accelerate medical breakthroughs.

Our Solutions

NovaCode Bio aims to pioneer a scalable, AI-driven platform for peptide discovery and delivery, leveraging non-canonical amino acids and advanced automation to target intracellular and CNS challenges, delivering precise peptide-based therapies across the blood-brain barrier to transform medicine.

Rapidly generate and optimize multi-cyclic peptide libraries.

Dramatically accelerate lead identification, reduce downstream attrition, and enable scalable, end-to-end automation.

Achieve targeted intracellular and blood-brain barrier penetration via precision-engineered nanocarriers.

NovaCode Bio Drug Discovery System

Four Pillars of Innovation

Non-canonical Amino Acids Unlock Novel Chemical Space

We employ over 200 non-canonical amino acids site-specifically incorporated into evolving peptide chains, creating unique functional handles and conformational constraints that enhance target.

200+ amino acids

Multi-cyclic Peptide Libraries for Enhanced Potency & Stability

Our platform constructs vast multi-cyclic peptide libraries via macrocyclization chemistries, delivering high screening success rates, enabling rapid hit discovery against intracellular and CNS targets in as little as weeks--versus years by traditional methods.

Weeks vs Years

Precision Nano-Delivery for Intracellular & CNS Access

Early automated, AI-centered integrable nanocarriers equipped with endosomal-escape and receptor-mediated-transport modules, achieving efficient cytosolic delivery and blood-brain-barrier transcytosis in preclinical models.

CNS Access

Fully Automated, AI-Accelerated Workflows

End-to-end automated system integrates combinatorial synthesis, high-throughput on-site in vitro and cellular assays, and closed-loop generative-AI design to optimize sequences for potency, permeability, and safety in real time.

AI-Driven

Successes of the platform - library screens to clinical trials

NCT03804424

64Cu-LLP2A PET Imaging in Diagnosing Patients with Multiple Myeloma.

NCT03197623

A Phase 1 Randomized, Double-Blind, Placebo-Controlled Single and Multiple Ascending Dose Study of the Safety and Tolerability of Intravenous LLP2A-Alendronate in Adult Men and Women with Osteopenia Secondary to Corticosteroids.

NCT06173349

Screening of OBOC peptide library identified the bladder cancer-targeting peptide ligand PLZ4. PLZ4-conjugated telodendrimer self-assembled into nanomicelle and efficiently loaded PTX.

Ready to Explore Our Innovation?

Discover how our revolutionary platforms can transform therapeutic development